Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants.

Using a large panel of human immunodeficiency virus type 1 site-directed mutants, we have observed a higher correlation than has previously been demonstrated between zidovudine (AZT)-triphosphate resistance data at the reverse transcriptase (RT) level and corresponding viral AZT resistance. This enh...

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Bibliographic Details
Main Authors: Lennerstrand, J, Hertogs, K, Stammers, D, Larder, B
Format: Journal article
Language:English
Published: 2001