Metabolomics of 293T IDH1 mutant and wild-type cells

These data were produced from the analysis of the 293T cells with (MUT) and without (WT) a transduced isocitrate dehydrogenase 1 (IDH1) mutation. The data were acquired as part of the project “Investigating Isocitrate Dehydrogenase Mutations in Cancer Using New Metabolomics Methods” using multiple l...

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Main Author: Walsby-Tickle, J
Other Authors: McCullagh, J
Format: Dataset
Language:English
Published: University of Oxford 2020
Subjects:
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author Walsby-Tickle, J
author2 McCullagh, J
author_facet McCullagh, J
Walsby-Tickle, J
author_sort Walsby-Tickle, J
collection OXFORD
description These data were produced from the analysis of the 293T cells with (MUT) and without (WT) a transduced isocitrate dehydrogenase 1 (IDH1) mutation. The data were acquired as part of the project “Investigating Isocitrate Dehydrogenase Mutations in Cancer Using New Metabolomics Methods” using multiple liquid chromatography-mass spectrometry methods. Anion-exchange chromatography-mass spectrometry (IC-MS) data were acquired on a Dionex IC-5000+ ion chromatography system hyphenated to a Thermo Fisher Scientific Exactive. Reversed-phase chromatography-mass spectrometry (RP-MS) data were acquired on a Dionex U3000 UHPLC system hyphenated to a Thermo Fisher Scientific Exactive. Derivatised RP-MS data were acquired on a Waters ACQUITY UPLC System hyphenated to a Waters Xevo G2-XS QTof with sample derivatisation using 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate. Data are .zip compressed to reduce file size. Data files in the .RAW format require Thermo Fisher Scientific Xcalibur software to analyse. Data folders in the .RAW format require Waters Masslynx software to analyse.
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spelling oxford-uuid:9a4d7231-9432-4a92-95ea-a7474f07d2652022-03-27T00:20:35ZMetabolomics of 293T IDH1 mutant and wild-type cellsDatasethttp://purl.org/coar/resource_type/c_ddb1uuid:9a4d7231-9432-4a92-95ea-a7474f07d265Mass spectrometryChemistryAnalysisEnglishORA4-prd-depositUniversity of Oxford2020Walsby-Tickle, JMcCullagh, JThese data were produced from the analysis of the 293T cells with (MUT) and without (WT) a transduced isocitrate dehydrogenase 1 (IDH1) mutation. The data were acquired as part of the project “Investigating Isocitrate Dehydrogenase Mutations in Cancer Using New Metabolomics Methods” using multiple liquid chromatography-mass spectrometry methods. Anion-exchange chromatography-mass spectrometry (IC-MS) data were acquired on a Dionex IC-5000+ ion chromatography system hyphenated to a Thermo Fisher Scientific Exactive. Reversed-phase chromatography-mass spectrometry (RP-MS) data were acquired on a Dionex U3000 UHPLC system hyphenated to a Thermo Fisher Scientific Exactive. Derivatised RP-MS data were acquired on a Waters ACQUITY UPLC System hyphenated to a Waters Xevo G2-XS QTof with sample derivatisation using 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate. Data are .zip compressed to reduce file size. Data files in the .RAW format require Thermo Fisher Scientific Xcalibur software to analyse. Data folders in the .RAW format require Waters Masslynx software to analyse.
spellingShingle Mass spectrometry
Chemistry
Analysis
Walsby-Tickle, J
Metabolomics of 293T IDH1 mutant and wild-type cells
title Metabolomics of 293T IDH1 mutant and wild-type cells
title_full Metabolomics of 293T IDH1 mutant and wild-type cells
title_fullStr Metabolomics of 293T IDH1 mutant and wild-type cells
title_full_unstemmed Metabolomics of 293T IDH1 mutant and wild-type cells
title_short Metabolomics of 293T IDH1 mutant and wild-type cells
title_sort metabolomics of 293t idh1 mutant and wild type cells
topic Mass spectrometry
Chemistry
Analysis
work_keys_str_mv AT walsbyticklej metabolomicsof293tidh1mutantandwildtypecells