The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

<p>Apurinic/apyrimidinic endonuclease 1 (APE1) is a key DNA repair factor involved in the DNA base excision repair (BER) pathway that is required for the maintenance of genome stability. In this pathway, APE1 cleaves DNA at an abasic site to generate a DNA single strand break, allowing for rep...

Ամբողջական նկարագրություն

Մատենագիտական մանրամասներ
Հիմնական հեղինակ:	Meisenberg, C
Այլ հեղինակներ:	Dianov, G
Ձևաչափ:	Թեզիս
Լեզու:	English
Հրապարակվել է:	2012
Խորագրեր:	DNA damage signalling Biology (medical sciences) Radiation Oncology

Նմանատիպ նյութեր

Apurinic/Apyrimidinic Endonuclease 1 and Tyrosyl-DNA Phosphodiesterase 1 Prevent Suicidal Covalent DNA-Protein Crosslink at Apurinic/Apyrimidinic Site
‌: Natalia A. Lebedeva, և այլն
Հրապարակվել է: (2021-01-01)

JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
‌: Tabanifar, Bahareh, և այլն
Հրապարակվել է: (2023)

Apurinic/apyrimidinic endonuclease 1 performs multiple roles in controlling the outcome of cancer cells toward radiation and chemotherapeutic agents
‌: Dindial Ramotar, և այլն
Հրապարակվել է: (2018-01-01)

JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
‌: Bahareh Tabanifar, և այլն
Հրապարակվել է: (2023-09-01)

Novel regulation of SRC family kinase signalling by RASSF1 isoforms
‌: Scrace, SF
Հրապարակվել է: (2013)

The role of genotype/phenotype at apurinic/apyrimidinic endonuclease Rs1130409 in renal cell carcinoma
‌: Cheng-Hsi Liao, և այլն
Հրապարակվել է: (2020-01-01)

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
‌: O'Brien, EM
Հրապարակվել է: (2012)

Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.
‌: Anton Simeonov, և այլն
Հրապարակվել է: (2009-06-01)

Activity of Human Apurinic/Apyrimidinic Endonuclease APE1 Toward Damaged DNA and Native RNA With Non-canonical Structures
‌: Anastasia T. Davletgildeeva, և այլն
Հրապարակվել է: (2020-10-01)

Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori.
‌: Aigerim Turgimbayeva, և այլն
Հրապարակվել է: (2018-01-01)

Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma
‌: Veronica Bazzani, և այլն
Հրապարակվել է: (2020-10-01)

Selective targeting of homologous recombination deficiency
‌: Zimmer, J
Հրապարակվել է: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
‌: Pfister, SX
Հրապարակվել է: (2014)

Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
‌: Braun Werner, և այլն
Հրապարակվել է: (2002-11-01)

Altered endoribonuclease activity of apurinic/apyrimidinic endonuclease 1 variants identified in the human population.
‌: Wan Cheol Kim, և այլն
Հրապարակվել է: (2014-01-01)

Cloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L.
‌: Botagoz Joldybayeva, և այլն
Հրապարակվել է: (2014-01-01)

Catalytic properties of human apurinic/apyrimidinic endonuclease 1 (APE1) and development of biosensors of APE1 in living cells
‌: Wang, Tianxiang
Հրապարակվել է: (2021)

Fluorogenic Aptamer-Based Hybridization Chain Reaction for Signal-Amplified Imaging of Apurinic/Apyrimidinic Endonuclease 1 in Living Cells
‌: Meixi Liu, և այլն
Հրապարակվել է: (2024-05-01)

Endonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damage.
‌: Rupangi Verma Puri, և այլն
Հրապարակվել է: (2013-01-01)

Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer.
‌: Joohyun Woo, և այլն
Հրապարակվել է: (2014-01-01)

The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1
‌: Anatoly A. Bulygin, և այլն
Հրապարակվել է: (2020-08-01)

Hypoxia-induced chromatin changes and ATM signalling
‌: Olcina del Molino, M
Հրապարակվել է: (2014)

Correction: Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L
Հրապարակվել է: (2014-01-01)

Correction: Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L.
Հրապարակվել է: (2014-01-01)

Base excision repair of radiation-induced DNA damage in mammalian cells
‌: Cooper, S, և այլն
Հրապարակվել է: (2013)

A specific DNA-nanoprobe for tracking the activities of human apurinic/apyrimidinic endonuclease 1 in living cells
‌: Zhai, J, և այլն
Հրապարակվել է: (2017)

Apurinic/apyrimidinic endonuclease 1 alleviates inflammation in fibroblast-like synoviocytes from patients with rheumatoid arthritis
‌: Ha-Reum Lee, և այլն
Հրապարակվել է: (2024-08-01)

Development of clinical biomarkers of DNA double strand breaks for cancer care
‌: Shah, K
Հրապարակվել է: (2012)

Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms
‌: Thais Teixeira Oliveira, և այլն
Հրապարակվել է: (2021-09-01)

Elevated Plasma Apurinic/Apyrimidinic Endonuclease 1/Redox Effector Factor-1 Levels in Refractory Kawasaki Disease
‌: Yu-Ran Lee, և այլն
Հրապարակվել է: (2022-01-01)

Real-time studies of DNA repair kinetics following low-LET short-pulse electron radiation
‌: Mendes de Oliveira Martins, CD
Հրապարակվել է: (2014)

The role of LATS1 in DNA damage signalling
‌: Latusek, R
Հրապարակվել է: (2012)

A DNA/RNA hybrid fluorescent probe for high-throughput quantification of the activity of human apurinic/apyrimidinic endonuclease 1 in subcellular extracts
‌: Peng Lu, և այլն
Հրապարակվել է: (2023-09-01)

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1
‌: Sui J, և այլն
Հրապարակվել է: (2014-11-01)

An analysis of the S. cerevisiae RMI1 gene
‌: Ashton, TM
Հրապարակվել է: (2010)

Apurinic/Apyrimidinic Endonuclease 1 Restricts the Internalization of Bacteria Into Human Intestinal Epithelial Cells Through the Inhibition of Rac1
‌: Gerco den Hartog, և այլն
Հրապարակվել է: (2021-02-01)

The Biological Role of Apurinic/Apyrimidinic Endonuclease1/Redox Factor-1 as a Therapeutic Target for Vascular Inflammation and as a Serologic Biomarker
‌: Yu Ran Lee, և այլն
Հրապարակվել է: (2020-03-01)

Visualization and Comparison of the Level of Apurinic/Apyrimidinic Endonuclease 1 in Live Normal/Cancerous and Neuron Cells with a Fluorescent Nanoprobe
‌: Peng Lu, և այլն
Հրապարակվել է: (2023-05-01)

Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line.
‌: Daria V Kim, և այլն
Հրապարակվել է: (2021-01-01)

Apurinic/apyrimidinic endonucleases of Mycobacterium tuberculosis protect against DNA damage but are dispensable for the growth of the pathogen in guinea pigs.
‌: Rupangi Verma Puri, և այլն
Հրապարակվել է: (2014-01-01)