The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

<p>Apurinic/apyrimidinic endonuclease 1 (APE1) is a key DNA repair factor involved in the DNA base excision repair (BER) pathway that is required for the maintenance of genome stability. In this pathway, APE1 cleaves DNA at an abasic site to generate a DNA single strand break, allowing for rep...

Descrizione completa

Dettagli Bibliografici
Autore principale:	Meisenberg, C
Altri autori:	Dianov, G
Natura:	Tesi
Lingua:	English
Pubblicazione:	2012
Soggetti:	DNA damage signalling Biology (medical sciences) Radiation Oncology

Documenti analoghi

Apurinic/Apyrimidinic Endonuclease 1 and Tyrosyl-DNA Phosphodiesterase 1 Prevent Suicidal Covalent DNA-Protein Crosslink at Apurinic/Apyrimidinic Site
di: Natalia A. Lebedeva, et al.
Pubblicazione: (2021-01-01)

JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
di: Tabanifar, Bahareh, et al.
Pubblicazione: (2023)

Apurinic/apyrimidinic endonuclease 1 performs multiple roles in controlling the outcome of cancer cells toward radiation and chemotherapeutic agents
di: Dindial Ramotar, et al.
Pubblicazione: (2018-01-01)

JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
di: Bahareh Tabanifar, et al.
Pubblicazione: (2023-09-01)

Novel regulation of SRC family kinase signalling by RASSF1 isoforms
di: Scrace, SF
Pubblicazione: (2013)

The role of genotype/phenotype at apurinic/apyrimidinic endonuclease Rs1130409 in renal cell carcinoma
di: Cheng-Hsi Liao, et al.
Pubblicazione: (2020-01-01)

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
di: O'Brien, EM
Pubblicazione: (2012)

Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.
di: Anton Simeonov, et al.
Pubblicazione: (2009-06-01)

Activity of Human Apurinic/Apyrimidinic Endonuclease APE1 Toward Damaged DNA and Native RNA With Non-canonical Structures
di: Anastasia T. Davletgildeeva, et al.
Pubblicazione: (2020-10-01)

Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori.
di: Aigerim Turgimbayeva, et al.
Pubblicazione: (2018-01-01)

Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma
di: Veronica Bazzani, et al.
Pubblicazione: (2020-10-01)

Selective targeting of homologous recombination deficiency
di: Zimmer, J
Pubblicazione: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
di: Pfister, SX
Pubblicazione: (2014)

Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
di: Braun Werner, et al.
Pubblicazione: (2002-11-01)

Altered endoribonuclease activity of apurinic/apyrimidinic endonuclease 1 variants identified in the human population.
di: Wan Cheol Kim, et al.
Pubblicazione: (2014-01-01)

Cloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L.
di: Botagoz Joldybayeva, et al.
Pubblicazione: (2014-01-01)

Catalytic properties of human apurinic/apyrimidinic endonuclease 1 (APE1) and development of biosensors of APE1 in living cells
di: Wang, Tianxiang
Pubblicazione: (2021)

Fluorogenic Aptamer-Based Hybridization Chain Reaction for Signal-Amplified Imaging of Apurinic/Apyrimidinic Endonuclease 1 in Living Cells
di: Meixi Liu, et al.
Pubblicazione: (2024-05-01)

Endonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damage.
di: Rupangi Verma Puri, et al.
Pubblicazione: (2013-01-01)

Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer.
di: Joohyun Woo, et al.
Pubblicazione: (2014-01-01)

The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1
di: Anatoly A. Bulygin, et al.
Pubblicazione: (2020-08-01)

Hypoxia-induced chromatin changes and ATM signalling
di: Olcina del Molino, M
Pubblicazione: (2014)

Correction: Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L
Pubblicazione: (2014-01-01)

Correction: Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L.
Pubblicazione: (2014-01-01)

Base excision repair of radiation-induced DNA damage in mammalian cells
di: Cooper, S, et al.
Pubblicazione: (2013)

A specific DNA-nanoprobe for tracking the activities of human apurinic/apyrimidinic endonuclease 1 in living cells
di: Zhai, J, et al.
Pubblicazione: (2017)

Apurinic/apyrimidinic endonuclease 1 alleviates inflammation in fibroblast-like synoviocytes from patients with rheumatoid arthritis
di: Ha-Reum Lee, et al.
Pubblicazione: (2024-08-01)

Development of clinical biomarkers of DNA double strand breaks for cancer care
di: Shah, K
Pubblicazione: (2012)

Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms
di: Thais Teixeira Oliveira, et al.
Pubblicazione: (2021-09-01)

Elevated Plasma Apurinic/Apyrimidinic Endonuclease 1/Redox Effector Factor-1 Levels in Refractory Kawasaki Disease
di: Yu-Ran Lee, et al.
Pubblicazione: (2022-01-01)

Real-time studies of DNA repair kinetics following low-LET short-pulse electron radiation
di: Mendes de Oliveira Martins, CD
Pubblicazione: (2014)

The role of LATS1 in DNA damage signalling
di: Latusek, R
Pubblicazione: (2012)

A DNA/RNA hybrid fluorescent probe for high-throughput quantification of the activity of human apurinic/apyrimidinic endonuclease 1 in subcellular extracts
di: Peng Lu, et al.
Pubblicazione: (2023-09-01)

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1
di: Sui J, et al.
Pubblicazione: (2014-11-01)

An analysis of the S. cerevisiae RMI1 gene
di: Ashton, TM
Pubblicazione: (2010)

Apurinic/Apyrimidinic Endonuclease 1 Restricts the Internalization of Bacteria Into Human Intestinal Epithelial Cells Through the Inhibition of Rac1
di: Gerco den Hartog, et al.
Pubblicazione: (2021-02-01)

The Biological Role of Apurinic/Apyrimidinic Endonuclease1/Redox Factor-1 as a Therapeutic Target for Vascular Inflammation and as a Serologic Biomarker
di: Yu Ran Lee, et al.
Pubblicazione: (2020-03-01)

Visualization and Comparison of the Level of Apurinic/Apyrimidinic Endonuclease 1 in Live Normal/Cancerous and Neuron Cells with a Fluorescent Nanoprobe
di: Peng Lu, et al.
Pubblicazione: (2023-05-01)

Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line.
di: Daria V Kim, et al.
Pubblicazione: (2021-01-01)

Apurinic/apyrimidinic endonucleases of Mycobacterium tuberculosis protect against DNA damage but are dispensable for the growth of the pathogen in guinea pigs.
di: Rupangi Verma Puri, et al.
Pubblicazione: (2014-01-01)