The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

<p>Apurinic/apyrimidinic endonuclease 1 (APE1) is a key DNA repair factor involved in the DNA base excision repair (BER) pathway that is required for the maintenance of genome stability. In this pathway, APE1 cleaves DNA at an abasic site to generate a DNA single strand break, allowing for rep...

書誌詳細
第一著者:	Meisenberg, C
その他の著者:	Dianov, G
フォーマット:	学位論文
言語:	English
出版事項:	2012
主題:	DNA damage signalling Biology (medical sciences) Radiation Oncology

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