The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

<p>Apurinic/apyrimidinic endonuclease 1 (APE1) is a key DNA repair factor involved in the DNA base excision repair (BER) pathway that is required for the maintenance of genome stability. In this pathway, APE1 cleaves DNA at an abasic site to generate a DNA single strand break, allowing for rep...

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Chi tiết về thư mục
Tác giả chính:	Meisenberg, C
Tác giả khác:	Dianov, G
Định dạng:	Luận văn
Ngôn ngữ:	English
Được phát hành:	2012
Những chủ đề:	DNA damage signalling Biology (medical sciences) Radiation Oncology

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