The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

The role of ubiquitylation in regulating apurinic/apyrimidinic endonuclease 1

<p>Apurinic/apyrimidinic endonuclease 1 (APE1) is a key DNA repair factor involved in the DNA base excision repair (BER) pathway that is required for the maintenance of genome stability. In this pathway, APE1 cleaves DNA at an abasic site to generate a DNA single strand break, allowing for rep...

書目詳細資料
主要作者:	Meisenberg, C
其他作者:	Dianov, G
格式:	Thesis
語言:	English
出版:	2012
主題:	DNA damage signalling Biology (medical sciences) Radiation Oncology

相似書籍

Apurinic/Apyrimidinic Endonuclease 1 and Tyrosyl-DNA Phosphodiesterase 1 Prevent Suicidal Covalent DNA-Protein Crosslink at Apurinic/Apyrimidinic Site
由: Natalia A. Lebedeva, et al.
出版: (2021-01-01)

JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
由: Tabanifar, Bahareh, et al.
出版: (2023)

Apurinic/apyrimidinic endonuclease 1 performs multiple roles in controlling the outcome of cancer cells toward radiation and chemotherapeutic agents
由: Dindial Ramotar, et al.
出版: (2018-01-01)

JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
由: Bahareh Tabanifar, et al.
出版: (2023-09-01)

Novel regulation of SRC family kinase signalling by RASSF1 isoforms
由: Scrace, SF
出版: (2013)

The role of genotype/phenotype at apurinic/apyrimidinic endonuclease Rs1130409 in renal cell carcinoma
由: Cheng-Hsi Liao, et al.
出版: (2020-01-01)

The role of Wee1 in the hypoxia-induced DNA damage response and its potential as a therapeutic target
由: O'Brien, EM
出版: (2012)

Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.
由: Anton Simeonov, et al.
出版: (2009-06-01)

Activity of Human Apurinic/Apyrimidinic Endonuclease APE1 Toward Damaged DNA and Native RNA With Non-canonical Structures
由: Anastasia T. Davletgildeeva, et al.
出版: (2020-10-01)

Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori.
由: Aigerim Turgimbayeva, et al.
出版: (2018-01-01)

Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma
由: Veronica Bazzani, et al.
出版: (2020-10-01)

Selective targeting of homologous recombination deficiency
由: Zimmer, J
出版: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
由: Pfister, SX
出版: (2014)

Total sequence decomposition distinguishes functional modules, "molegos" in apurinic/apyrimidinic endonucleases
由: Braun Werner, et al.
出版: (2002-11-01)

Altered endoribonuclease activity of apurinic/apyrimidinic endonuclease 1 variants identified in the human population.
由: Wan Cheol Kim, et al.
出版: (2014-01-01)

Cloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L.
由: Botagoz Joldybayeva, et al.
出版: (2014-01-01)

Catalytic properties of human apurinic/apyrimidinic endonuclease 1 (APE1) and development of biosensors of APE1 in living cells
由: Wang, Tianxiang
出版: (2021)

Fluorogenic Aptamer-Based Hybridization Chain Reaction for Signal-Amplified Imaging of Apurinic/Apyrimidinic Endonuclease 1 in Living Cells
由: Meixi Liu, et al.
出版: (2024-05-01)

Endonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damage.
由: Rupangi Verma Puri, et al.
出版: (2013-01-01)

Prognostic value of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in breast cancer.
由: Joohyun Woo, et al.
出版: (2014-01-01)

The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1
由: Anatoly A. Bulygin, et al.
出版: (2020-08-01)

Hypoxia-induced chromatin changes and ATM signalling
由: Olcina del Molino, M
出版: (2014)

Correction: Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L
出版: (2014-01-01)

Correction: Cloning and Characterization of a Wheat Homologue of Apurinic/Apyrimidinic Endonuclease Ape1L.
出版: (2014-01-01)

Base excision repair of radiation-induced DNA damage in mammalian cells
由: Cooper, S, et al.
出版: (2013)

A specific DNA-nanoprobe for tracking the activities of human apurinic/apyrimidinic endonuclease 1 in living cells
由: Zhai, J, et al.
出版: (2017)

Apurinic/apyrimidinic endonuclease 1 alleviates inflammation in fibroblast-like synoviocytes from patients with rheumatoid arthritis
由: Ha-Reum Lee, et al.
出版: (2024-08-01)

Development of clinical biomarkers of DNA double strand breaks for cancer care
由: Shah, K
出版: (2012)

Chemical Inhibition of Apurinic-Apyrimidinic Endonuclease 1 Redox and DNA Repair Functions Affects the Inflammatory Response via Different but Overlapping Mechanisms
由: Thais Teixeira Oliveira, et al.
出版: (2021-09-01)

Elevated Plasma Apurinic/Apyrimidinic Endonuclease 1/Redox Effector Factor-1 Levels in Refractory Kawasaki Disease
由: Yu-Ran Lee, et al.
出版: (2022-01-01)

Real-time studies of DNA repair kinetics following low-LET short-pulse electron radiation
由: Mendes de Oliveira Martins, CD
出版: (2014)

The role of LATS1 in DNA damage signalling
由: Latusek, R
出版: (2012)

A DNA/RNA hybrid fluorescent probe for high-throughput quantification of the activity of human apurinic/apyrimidinic endonuclease 1 in subcellular extracts
由: Peng Lu, et al.
出版: (2023-09-01)

Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1
由: Sui J, et al.
出版: (2014-11-01)

An analysis of the S. cerevisiae RMI1 gene
由: Ashton, TM
出版: (2010)

Apurinic/Apyrimidinic Endonuclease 1 Restricts the Internalization of Bacteria Into Human Intestinal Epithelial Cells Through the Inhibition of Rac1
由: Gerco den Hartog, et al.
出版: (2021-02-01)

The Biological Role of Apurinic/Apyrimidinic Endonuclease1/Redox Factor-1 as a Therapeutic Target for Vascular Inflammation and as a Serologic Biomarker
由: Yu Ran Lee, et al.
出版: (2020-03-01)

Visualization and Comparison of the Level of Apurinic/Apyrimidinic Endonuclease 1 in Live Normal/Cancerous and Neuron Cells with a Fluorescent Nanoprobe
由: Peng Lu, et al.
出版: (2023-05-01)

Mild phenotype of knockouts of the major apurinic/apyrimidinic endonuclease APEX1 in a non-cancer human cell line.
由: Daria V Kim, et al.
出版: (2021-01-01)

Apurinic/apyrimidinic endonucleases of Mycobacterium tuberculosis protect against DNA damage but are dispensable for the growth of the pathogen in guinea pigs.
由: Rupangi Verma Puri, et al.
出版: (2014-01-01)