Penicillin derivatives inhibit the SARS-CoV-2 main protease by reaction with its nucleophilic cysteine

Ítems similars

• Alkyne derivatives of SARS-CoV-2 main protease inhibitors including nirmatrelvir inhibit by reacting covalently with the nucleophilic cysteine
  per: Brewitz, L, et al.
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• Mechanistic and inhibition studies on a nucleophilic cysteine protease and transpeptidases
  per: Malla, TR
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• In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease
  per: Miura, T, et al.
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• Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein
  per: Chan, HTH, et al.
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• Mass spectrometric assays monitoring the deubiquitinase activity of the SARS-CoV-2 papain-like protease inform on the basis of substrate selectivity and have utility for substrate identification
  per: Brewitz, L, et al.
  Publicat: (2023)