Penicillin derivatives inhibit the SARS-CoV-2 main protease by reaction with its nucleophilic cysteine

Παρόμοια τεκμήρια

• Alkyne derivatives of SARS-CoV-2 main protease inhibitors including nirmatrelvir inhibit by reacting covalently with the nucleophilic cysteine
  ανά: Brewitz, L, κ.ά.
  Έκδοση: (2023)
• Mechanistic and inhibition studies on a nucleophilic cysteine protease and transpeptidases
  ανά: Malla, TR
  Έκδοση: (2022)
• In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease
  ανά: Miura, T, κ.ά.
  Έκδοση: (2023)
• Studies on the selectivity of the SARS-CoV-2 papain-like protease reveal the importance of the P2' proline of the viral polyprotein
  ανά: Chan, HTH, κ.ά.
  Έκδοση: (2023)
• Mass spectrometric assays monitoring the deubiquitinase activity of the SARS-CoV-2 papain-like protease inform on the basis of substrate selectivity and have utility for substrate identification
  ανά: Brewitz, L, κ.ά.
  Έκδοση: (2023)