Simple detection of point mutations associated with HIV-1 drug resistance.

Simple detection of point mutations associated with HIV-1 drug resistance.

A novel assay is described for the detection of HIV-1 drug resistance that is simple, cheap and sensitive. HIV-1 drug resistance in B and non-B HIV-1 subtypes was investigated using Mutagenically-Separated PCR (MS--PCR) --- a competitive semi-nested PCR which uses mutagenic primers. The assay was as...

Description complète

Détails bibliographiques
Auteurs principaux:	Frater, A, Chaput, C, Beddows, S, Weber, J, McClure, M
Format:	Journal article
Langue:	English
Publié:	2001

Documents similaires

HIV-1 resistance genotyping by sequencing produces inconsistent results for mixed viral populations.
par: Frater, A, et autres
Publié: (2000)

Performance of two commercially available sequence-based HIV-1 genotyping systems for the detection of drug resistance against HIV type 1 group M subtypes.
par: Beddows, S, et autres
Publié: (2003)

Association between secondary mutations in human immunodeficiency virus type 1 protease and therapeutic outcome.
par: Frater, J, et autres
Publié: (2002)

HIV-1 drug resistance in primary infections in the UK.
par: Fidler, S, et autres
Publié: (2001)

Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease
par: Zhang, Tian-hao, et autres
Publié: (2021)

Comparative response of African HIV-1-infected individuals to highly active antiretroviral therapy.
par: Frater, A, et autres
Publié: (2002)

Protective HLA class I alleles are associated with reduced immune activation and fibrinolysis in individuals with primary HIV infection
par: Hamlyn, E, et autres
Publié: (2010)

HIV clearance in infants.
par: McClure, M, et autres
Publié: (1996)

The detection of pfcrt and pfmdr1 point mutations as molecular markers of chloroquine drug resistance, Pahang, Malaysia
par: Atroosh, W.M., et autres
Publié: (2012)

Identification of drug resistance mutations in HIV from constraints on natural evolution
par: Barton, John P., et autres
Publié: (2016)

Impact of baseline polymorphisms in RT and protease on outcome of highly active antiretroviral therapy in HIV-1-infected African patients.
par: Frater, A, et autres
Publié: (2001)

Prevalence of HIV type-1 drug-associated mutations in pre-therapy patients in the Free State, South Africa.
par: Huang, K, et autres
Publié: (2009)

Mutagenically separated PCR assay for rapid detection of M41L and K70R zidovudine resistance mutations in CRF01_AE (subtype E) human immunodeficiency virus type 1.
par: Myint, L, et autres
Publié: (2002)

Characterisation of circulatiing HIV-1 subtypes and drug resistance-associated mutations in protease and reverse transcriptase genes among HIV-1 patients in Kelantan
par: Tengku Mohd Ariffin, Tengku Ahmad Akram
Publié: (2015)

Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance
par: Rodwell, T, et autres
Publié: (2021)

Association of streptomycin resistance mutations with level of drug resistance and Mycobacterium tuberculosis genotypes.
par: Nhu, N, et autres
Publié: (2012)

Development and evaluation of the oligonucleotide ligation assay (OLA) for the detection of drug resistance mutations in HIV-2 patients on antiretroviral therapy
par: Jallow, S, et autres
Publié: (2006)

Closing in on HIV drug resistance.
par: Larder, B, et autres
Publié: (1999)

Hepatitis B virus drug resistance mutation detection by pyrosequencing method
par: Toh, Kim Pern.
Publié: (2013)

Phylogenetic analysis consistent with a clinical history of sexual transmission of HIV-1 from a single donor reveals transmission of highly distinct variants.
par: English, S, et autres
Publié: (2011)

Tuberculosis Drug Resistance Mutation Database
par: Sandgren, Andreas, et autres
Publié: (2010)

A point mutation in CD45 may be associated with an increased risk of HIV-1 infection.
par: Tchilian, E, et autres
Publié: (2001)

A point mutation in CD45 may be associated with an increased risk of HIV-1 infection
par: Tchilian, E, et autres
Publié: (2001)

Structural basis for the resilience of efavirenz (DMP-266) to drug resistance mutations in HIV-1 reverse transcriptase.
par: Ren, J, et autres
Publié: (2000)

Low prevalence of genotypic drug resistance mutations among antiretroviral-naive HIV type 1 patients in Malaysia
par: Tee, K.K., et autres
Publié: (2006)

Likely role of APOBEC3G-mediated G-to-A mutations in HIV-1 evolution and drug resistance.
par: Jern, P, et autres
Publié: (2009)

Gregory the Great
par: McClure, J, et autres
Publié: (1979)

Virological and immunological response to Combivir and emergence of drug resistance mutations in a cohort of HIV-2 patients in The Gambia.
par: Jallow, S, et autres
Publié: (2006)

Hepatitis B virus drug resistance mutations in HIV/HBV co-infected children in Windhoek, Namibia
par: Tamandjou Tchuem, CR, et autres
Publié: (2020)

Baseline polymorphisms found in patients infected with non-clade BHIV-1 do not affect outcome to HAART
par: Frater, A, et autres
Publié: (2000)

Increased levels of CD4 T-cell activation in individuals with CXCR4 using viruses in primary HIV-1 infection.
par: Hamlyn, E, et autres
Publié: (2012)

Prevalence and pattern of drug resistance mutations among antiretroviral-treated HIV-1 patients with suboptimal virological response in Malaysia
par: Tee, K.K., et autres
Publié: (2006)

Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138.
par: Ren, J, et autres
Publié: (2006)

Nevertheless, she resisted: the body as a site of resistance in "The Autopsy of Jane Doe"
par: Beddows, Amy
Publié: (2018)

Duration of HIV-1 viral suppression on cessation of antiretroviral therapy in primary infection correlates with time on therapy
par: Stöhr, W, et autres
Publié: (2013)

Mutations associated with genotypic resistance to antiretroviral therapy in treatment naive HIV-1 infected patients in Greece.
par: Magiorkinis, E, et autres
Publié: (2002)

HIV-1 drug resistance in antiretroviral-naive individuals with HIV-1-associated tuberculous meningitis initiating antiretroviral therapy in Vietnam.
par: Thao, V, et autres
Publié: (2012)

Development and evaluation of an oligonucleotide ligation assay for detection of drug resistance-associated mutations in the human immunodeficiency virus type 2 pol gene.
par: Jallow, S, et autres
Publié: (2007)

The role of the gut mucosa in protection from HIV-1 in highly exposed persistently seronegative individuals (HEPS)
par: Fox, J, et autres
Publié: (2009)

The effect of intrinsic stochasticity on transmitted HIV drug resistance patterns
par: Marks, A, et autres
Publié: (2010)