Life expectancy in patients attending multiple sclerosis clinics.
One multiple sclerosis (MS) is diagnosed, important considerations often include life expectancy and the availability of life insurance. We designed a study specifically to examine life expectancy among MS clinic patients and analyzed the data using standard actuarial methods, both including and exc...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
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1992
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| _version_ | 1797084270574960640 |
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| author | Sadovnick, A Ebers, G Wilson, R Paty, D |
| author_facet | Sadovnick, A Ebers, G Wilson, R Paty, D |
| author_sort | Sadovnick, A |
| collection | OXFORD |
| description | One multiple sclerosis (MS) is diagnosed, important considerations often include life expectancy and the availability of life insurance. We designed a study specifically to examine life expectancy among MS clinic patients and analyzed the data using standard actuarial methods, both including and excluding suicides. The data show that severe MS disability, as measured by an Expanded Disability Status Score (EDSS) of greater than or equal to 7.5, is a major risk factor for death with case fatality ratios for this group of patients approaching 4 times the rate for controls. Conversely, excluding deaths by suicide, case fatality ratios for those with mild and moderate disability (EDSS less than or equal to 7.0) approach 1.4 times and 1.6 times for age- and sex-matched comparison groups. Life tables indicate that the overall life expectancy for MS is only about 6 to 7 years less than that for the "insured" population without MS. |
| first_indexed | 2024-03-07T01:53:06Z |
| format | Journal article |
| id | oxford-uuid:9acae5ca-6e34-4a93-833e-70e09134a7a3 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:53:06Z |
| publishDate | 1992 |
| record_format | dspace |
| spelling | oxford-uuid:9acae5ca-6e34-4a93-833e-70e09134a7a32022-03-27T00:23:50ZLife expectancy in patients attending multiple sclerosis clinics.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9acae5ca-6e34-4a93-833e-70e09134a7a3EnglishSymplectic Elements at Oxford1992Sadovnick, AEbers, GWilson, RPaty, DOne multiple sclerosis (MS) is diagnosed, important considerations often include life expectancy and the availability of life insurance. We designed a study specifically to examine life expectancy among MS clinic patients and analyzed the data using standard actuarial methods, both including and excluding suicides. The data show that severe MS disability, as measured by an Expanded Disability Status Score (EDSS) of greater than or equal to 7.5, is a major risk factor for death with case fatality ratios for this group of patients approaching 4 times the rate for controls. Conversely, excluding deaths by suicide, case fatality ratios for those with mild and moderate disability (EDSS less than or equal to 7.0) approach 1.4 times and 1.6 times for age- and sex-matched comparison groups. Life tables indicate that the overall life expectancy for MS is only about 6 to 7 years less than that for the "insured" population without MS. |
| spellingShingle | Sadovnick, A Ebers, G Wilson, R Paty, D Life expectancy in patients attending multiple sclerosis clinics. |
| title | Life expectancy in patients attending multiple sclerosis clinics. |
| title_full | Life expectancy in patients attending multiple sclerosis clinics. |
| title_fullStr | Life expectancy in patients attending multiple sclerosis clinics. |
| title_full_unstemmed | Life expectancy in patients attending multiple sclerosis clinics. |
| title_short | Life expectancy in patients attending multiple sclerosis clinics. |
| title_sort | life expectancy in patients attending multiple sclerosis clinics |
| work_keys_str_mv | AT sadovnicka lifeexpectancyinpatientsattendingmultiplesclerosisclinics AT ebersg lifeexpectancyinpatientsattendingmultiplesclerosisclinics AT wilsonr lifeexpectancyinpatientsattendingmultiplesclerosisclinics AT patyd lifeexpectancyinpatientsattendingmultiplesclerosisclinics |