The use of monoclonal antibodies to achieve immunological tolerance.
Monoclonal antibodies are potentially useful immunosuppressive agents. Short courses of CD4/CD8 monoclonal antibody can be used to guide the immune system of experimental animals to accept organ grafts and to arrest autoimmunity. This reprogramming is accompanied by potent T-cell dependent, 'in...
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Bibliographic Details
Main Authors: |
Waldmann, H,
Cobbold, S |
Format: | Journal article
|
Language: | English |
Published: |
1993
|