Airway and blood monocyte transcriptomic profiling reveals an antiviral phenotype in infants with severe respiratory syncytial virus infection
<strong>Background<br></strong> Respiratory syncytial virus (RSV) infection is the primary cause of lower respiratory tract infections in children <5 years of age. Monocytes, especially in the respiratory tract, are suggested to contribute to RSV pathology, but their role is inc...
Main Authors: | Chappin, K, Besteman, SB, Hennus, MP, Wildenbeest, JG, Mokry, M, Bont, LJ, van der Vlist, M, Calis, JJA, Pollard, AJ |
---|---|
Other Authors: | PROMISE Investigators |
Format: | Journal article |
Language: | English |
Published: |
Oxford University Press
2024
|
Similar Items
-
The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study
by: Wildenbeest, JG, et al.
Published: (2022) -
Respiratory Syncytial Virus Consortium in Europe (RESCEU) birth cohort study: defining the burden of infant respiratory syncytial virus disease in Europe
by: Wildenbeest, JG, et al.
Published: (2020) -
Patient involvement in RSV research: towards patients setting the research agenda
by: Derksen-Lazet, ND, et al.
Published: (2022) -
Clinical and viral factors associated with disease severity and subsequent wheezing in infants with respiratory syncytial virus infection
by: McGinley, JP, et al.
Published: (2022) -
Single-cell immune profiling reveals markers of emergency myelopoiesis that distinguish severe from mild respiratory syncytial virus disease in infants
by: Zivanovic, N, et al.
Published: (2023)