Roles for CEP170 in cilia function and dynein-2 assembly
Primary cilia are essential eukaryotic organelles required for signalling and secretion. Dynein-2 is a microtubule-motor protein complex and is required for ciliogenesis via its role in facilitating retrograde intraflagellar transport (IFT) from the cilia tip to the cell body. Dynein-2 must be assem...
Main Authors: | Weijman, JF, Vuolo, L, Shak, C, Pugnetti, A, Mukhopadhyay, AG, Hodgson, LR, Heesom, KJ, Roberts, AJ, Stephens, DJ |
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Format: | Journal article |
Language: | English |
Published: |
The Company of Biologists
2024
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