Small GTPases and LFA-1 reciprocally modulate adhesion and signaling.
Leukocyte-function-associated antigen-1 (LFA-1) is an integrin that is critical for T-cell adhesion and immunologic responses. As a transmembrane receptor and adhesion molecule, LFA-1 signals bidirectionally, whereby information about extracellular ligands is passed outside-in while cellular activat...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2007
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