Identification of tuberculosis susceptibility genes with human macrophage gene expression profiles.

Although host genetics influences susceptibility to tuberculosis (TB), few genes determining disease outcome have been identified. We hypothesized that macrophages from individuals with different clinical manifestations of Mycobacterium tuberculosis (Mtb) infection would have distinct gene expressio...

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Détails bibliographiques
Auteurs principaux: Thuong, N, Dunstan, S, Chau, T, Thorsson, V, Simmons, C, Quyen, N, Thwaites, G, Thi Ngoc Lan, N, Hibberd, M, Teo, Y, Seielstad, M, Aderem, A, Farrar, J, Hawn, T
Format: Journal article
Langue:English
Publié: Public Library of Science 2008