Dephosphorylated polymerase I and transcript release factor prevents allergic asthma exacerbations by limiting IL-33 release

Background: Asthma is a chronic inflammatory disease characterized by airway inflammation and airway hyperresponsiveness (AHR). IL-33 is considered as one of the most critical molecules in asthma pathogenesis. IL-33 is stored in nucleus and passively released during necrosis. But little is known abo...

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Bibliographic Details
Main Authors: Ni, Y, Hao, J, Hou, X, Du, W, Yu, Y, Chen, T, Wei, Z, Li, Y, Zhu, F, Wang, S, Liang, R, Li, D, Lu, Y, Liao, K, Li, B, Shi, G
Format: Journal article
Language:English
Published: Frontiers Media 2018