Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers.
Oseltamivir and oseltamivir carboxylate concentrations were measured in venous plasma, venous blood, and capillary blood taken simultaneously from 24 healthy volunteers. Median (range) venous-blood-to-plasma ratios were 1.42 (0.920 to 1.97) for oseltamivir and 0.673 (0.564 to 0.814) for oseltamivir...
| 主要な著者: | , , , , , , , |
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| フォーマット: | Journal article |
| 言語: | English |
| 出版事項: |
2013
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| _version_ | 1826287229445603328 |
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| author | Instiaty, I Lindegardh, N Jittmala, P Hanpithakpong, W Blessborn, D Pukrittayakamee, S White, N Tarning, J |
| author_facet | Instiaty, I Lindegardh, N Jittmala, P Hanpithakpong, W Blessborn, D Pukrittayakamee, S White, N Tarning, J |
| author_sort | Instiaty, I |
| collection | OXFORD |
| description | Oseltamivir and oseltamivir carboxylate concentrations were measured in venous plasma, venous blood, and capillary blood taken simultaneously from 24 healthy volunteers. Median (range) venous-blood-to-plasma ratios were 1.42 (0.920 to 1.97) for oseltamivir and 0.673 (0.564 to 0.814) for oseltamivir carboxylate. Capillary blood/venous plasma ratios were 1.32 (0.737 to 3.16) for oseltamivir and 0.685 (0.502 to 1.34) for oseltamivir carboxylate. Oseltamivir concentrations in venous and capillary blood were similar. Oseltamivir carboxylate showed a time-dependent distribution between venous and capillary blood. |
| first_indexed | 2024-03-07T01:55:30Z |
| format | Journal article |
| id | oxford-uuid:9b925def-cf2e-4be7-9aa1-5169a6883f46 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:55:30Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:9b925def-cf2e-4be7-9aa1-5169a6883f462022-03-27T00:29:46ZComparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9b925def-cf2e-4be7-9aa1-5169a6883f46EnglishSymplectic Elements at Oxford2013Instiaty, ILindegardh, NJittmala, PHanpithakpong, WBlessborn, DPukrittayakamee, SWhite, NTarning, JOseltamivir and oseltamivir carboxylate concentrations were measured in venous plasma, venous blood, and capillary blood taken simultaneously from 24 healthy volunteers. Median (range) venous-blood-to-plasma ratios were 1.42 (0.920 to 1.97) for oseltamivir and 0.673 (0.564 to 0.814) for oseltamivir carboxylate. Capillary blood/venous plasma ratios were 1.32 (0.737 to 3.16) for oseltamivir and 0.685 (0.502 to 1.34) for oseltamivir carboxylate. Oseltamivir concentrations in venous and capillary blood were similar. Oseltamivir carboxylate showed a time-dependent distribution between venous and capillary blood. |
| spellingShingle | Instiaty, I Lindegardh, N Jittmala, P Hanpithakpong, W Blessborn, D Pukrittayakamee, S White, N Tarning, J Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers. |
| title | Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers. |
| title_full | Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers. |
| title_fullStr | Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers. |
| title_full_unstemmed | Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers. |
| title_short | Comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma, venous blood, and capillary blood in healthy volunteers. |
| title_sort | comparison of oseltamivir and oseltamivir carboxylate concentrations in venous plasma venous blood and capillary blood in healthy volunteers |
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