Collagen-induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade.

OBJECTIVE: There is a disparity in the animal models used to study pain in rheumatoid arthritis (RA), which tends to be acute in nature, and models used to assess the pathogenesis of RA. The latter models, like human RA, are lymphocyte-driven and polyarthritic. We assessed pain behavior and mechani...

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Bibliographic Details
Main Authors: Inglis, J, Notley, C, Essex, D, Wilson, A, Feldmann, M, Anand, P, Williams, R
Format: Journal article
Language:English
Published: 2007