Gout in pediatric renal transplant recipients.
Clinical gout has rarely been described after pediatric renal transplantation (RTx), although asymptomatic hyperuricemia is common in these patients. We describe three male pediatric patients who presented with gouty arthritis 7-8.5 years following RTx. Since receiving allopurinol, all patients had...
| Main Authors: | , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2010
|
| _version_ | 1797084510923259904 |
|---|---|
| author | Trück, J Laube, G von Vigier, R Goetschel, P |
| author_facet | Trück, J Laube, G von Vigier, R Goetschel, P |
| author_sort | Trück, J |
| collection | OXFORD |
| description | Clinical gout has rarely been described after pediatric renal transplantation (RTx), although asymptomatic hyperuricemia is common in these patients. We describe three male pediatric patients who presented with gouty arthritis 7-8.5 years following RTx. Since receiving allopurinol, all patients had been free of gouty symptoms. To prevent severe bone marrow depletion, the dosage of azathioprine, an immunosupressant drug, was reduced by 50% to prevent interaction with allopurinol. Because atypical presentation of gout can occur, a high index of suspicion is needed to allow appropriate diagnosis of this disease in patients with skeletal pain after RTx. |
| first_indexed | 2024-03-07T01:56:07Z |
| format | Journal article |
| id | oxford-uuid:9bc3ea53-62cc-4c42-a68b-727ae378d868 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:56:07Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:9bc3ea53-62cc-4c42-a68b-727ae378d8682022-03-27T00:31:11ZGout in pediatric renal transplant recipients.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9bc3ea53-62cc-4c42-a68b-727ae378d868EnglishSymplectic Elements at Oxford2010Trück, JLaube, Gvon Vigier, RGoetschel, PClinical gout has rarely been described after pediatric renal transplantation (RTx), although asymptomatic hyperuricemia is common in these patients. We describe three male pediatric patients who presented with gouty arthritis 7-8.5 years following RTx. Since receiving allopurinol, all patients had been free of gouty symptoms. To prevent severe bone marrow depletion, the dosage of azathioprine, an immunosupressant drug, was reduced by 50% to prevent interaction with allopurinol. Because atypical presentation of gout can occur, a high index of suspicion is needed to allow appropriate diagnosis of this disease in patients with skeletal pain after RTx. |
| spellingShingle | Trück, J Laube, G von Vigier, R Goetschel, P Gout in pediatric renal transplant recipients. |
| title | Gout in pediatric renal transplant recipients. |
| title_full | Gout in pediatric renal transplant recipients. |
| title_fullStr | Gout in pediatric renal transplant recipients. |
| title_full_unstemmed | Gout in pediatric renal transplant recipients. |
| title_short | Gout in pediatric renal transplant recipients. |
| title_sort | gout in pediatric renal transplant recipients |
| work_keys_str_mv | AT truckj goutinpediatricrenaltransplantrecipients AT laubeg goutinpediatricrenaltransplantrecipients AT vonvigierr goutinpediatricrenaltransplantrecipients AT goetschelp goutinpediatricrenaltransplantrecipients |