An open-label study of the safety and tolerability of pazopanib in combination with FOLFOX6 or CapeOx in patients with colorectal cancer

Background Although combining targeted agents with conventional, first-line cytotoxic therapy has improved survival outcomes in patients with advanced colorectal cancer, further improvements in outcomes and tolerability are needed. Methods This phase I study evaluated the feasibility of combining or...

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Những tác giả chính: Brady, J, Corrie, P, Chau, I, Digumarti, R, Adams, L, Botbyl, J, Laubscher, K, Midgley, R, Mallath, M
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2013