Assembly and crystallization of the complex between the human T cell coreceptor CD8alpha homodimer and HLA-A2.

Assembly and crystallization of the complex between the human T cell coreceptor CD8alpha homodimer and HLA-A2.

A strategy for overexpression in Escherichia coli of the extracellular immunoglobulin domain of human CD8alpha was devised using codon usage alterations in the 5' region of the gene, designed so as to prevent the formation of secondary structures in the mRNA. A fragment of CD8alpha, comprising...

Podrobná bibliografie
Hlavní autoři:	Gao, G, Gerth, U, Wyer, JR, Willcox, B, O'Callaghan, C, Zhang, Z, Jones, E, Bell, J, Jakobsen, B
Médium:	Journal article
Jazyk:	English
Vydáno:	1998

Podobné jednotky

T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics.
Autor: Wyer, JR, a další
Vydáno: (1999)

Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2.
Autor: Gao, G, a další
Vydáno: (1997)

Crystal structure of the complex between CD8αα human and HLA-A2
Autor: Gao, G, a další
Vydáno: (1997)

Production, crystallization, and preliminary X-ray analysis of the human MHC class Ib molecule HLA-E.
Autor: O'Callaghan, C, a další
Vydáno: (1998)

Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure.
Autor: Allen, R, a další
Vydáno: (1999)

BirA enzyme: production and application in the study of membrane receptor-ligand interactions by site-specific biotinylation.
Autor: O'Callaghan, C, a další
Vydáno: (1999)

Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha.
Autor: Gao, G, a další
Vydáno: (2000)

Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Autor: O'Callaghan, C, a další
Vydáno: (1998)

Structure and function of the human MHC class Ib molecules HLA-E, HLA-F and HLA-G.
Autor: O'Callaghan, C, a další
Vydáno: (1998)

Identification and characterisation of cell surface HLA-B27 homodimers
Autor: Bird, L, a další
Vydáno: (2002)

Production of soluble alphabeta T-cell receptor heterodimers suitable for biophysical analysis of ligand binding.
Autor: Willcox, B, a další
Vydáno: (1999)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
Autor: Bowness, P, a další
Vydáno: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
Autor: Bowness, P, a další
Vydáno: (2010)

Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondylarthritis.
Autor: Payeli, S, a další
Vydáno: (2012)

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers.
Autor: Kollnberger, S, a další
Vydáno: (2002)

Enhanced effect of the immunosuppressive soluble HLA-G2 homodimer by site-specific PEGylation
Autor: Chisato Yamada, a další
Vydáno: (2025-01-01)

HLA-B*2709, A SUBTYPE NOT ASSOCIATED WITH ANKYLOSING SPONDYLITIS, FORMS FEWER HOMODIMERS THAN HLA-B*2705
Autor: Giles, J, a další
Vydáno: (2010)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
Autor: Bowness, P, a další
Vydáno: (2003)

Selective HIV-1-induced downmodulation of CD4 and coreceptors.
Autor: Chenine, A, a další
Vydáno: (2000)

Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy.
Autor: Siebold, C, a další
Vydáno: (2004)

HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats.
Autor: Osiris Marroquin Belaunzaran, a další
Vydáno: (2015-01-01)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
Autor: McHugh, K, a další
Vydáno: (2008)

The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain.
Autor: Purbhoo, M, a další
Vydáno: (2001)

HIV-1-CD4-coreceptor interactions in virus binding and neutralization
Autor: Sattentau, Q, a další
Vydáno: (1998)

Induction of T cell adhesion by antigen stimulation and modulation by the coreceptor CD4.
Autor: Michel, F, a další
Vydáno: (1996)

Natural killer cell surveillance of intracellular antigen processing pathways mediated by recognition of HLA-E and Qa-1b by CD94/NKG2 receptors.
Autor: O'Callaghan, C
Vydáno: (2000)

Insights to HIV-1 coreceptor usage by estimating HLA adaptation with Bayesian generalized linear mixed models.
Autor: Anna Hake, a další
Vydáno: (2023-12-01)

Tetrameric complexes of HLA-E, HLA-F, and HLA-G.
Autor: Allan, D, a další
Vydáno: (2002)

The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells.
Autor: Kaizuka, Y, a další
Vydáno: (2009)

Antagonist HIV-1 Gag peptides induce structural changes in HLA B8.
Autor: Reid, S, a další
Vydáno: (1996)

HLA B27 can form heavy chain homodimers in vivo and in vivo, possible role of cys 67.
Autor: Bowness, P, a další
Vydáno: (1998)

The role of cell surface HLA-B27 heavy chain homodimer interactions with NK receptors in the pathogenesis of spondyloarthritis
Autor: Kollnberger, S
Vydáno: (2005)

Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.
Autor: Bird, L, a další
Vydáno: (2003)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
Autor: Giles, J, a další
Vydáno: (2008)

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
Autor: Kollnberger, S, a další
Vydáno: (2004)

An altered position of the alpha 2 helix of MHC class I is revealed by the crystal structure of HLA-B*3501.
Autor: Smith, K, a další
Vydáno: (1996)

Coreceptors and TCR signaling — the strong and the weak of it
Autor: Mørch, AM, a další
Vydáno: (2020)

Coreceptors and TCR Signaling – the Strong and the Weak of It
Autor: Alexander M. Mørch, a další
Vydáno: (2020-10-01)

HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I.
Autor: Giles, J, a další
Vydáno: (2012)

TCR binding to peptide-MHC stabilizes a flexible recognition interface.
Autor: Willcox, B, a další
Vydáno: (1999)