Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.

Invariant NKT cells reduce the immunosuppressive activity of influenza A virus-induced myeloid-derived suppressor cells in mice and humans.

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Infection with influenza A virus (IAV) presents a substantial threat to public health worldwide, with young, elderly, and immunodeficient individuals being particularly susceptible. Inflammatory responses play an important role in the fatal outcome of IAV infection, but the mechanism remains unclear...

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Bibliographic Details
Main Authors:	De Santo, C, Salio, M, Masri, S, Lee, L, Dong, T, Speak, A, Porubsky, S, Booth, S, Veerapen, N, Besra, G, Gröne, H, Platt, F, Zambon, M, Cerundolo, V
Format:	Journal article
Language:	English
Published:	2008

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