MHC class II proteins and disease: a structural perspective
MHC class II molecules on the surface of antigen-presenting cells display a range of peptides for recognition by the T-cell receptors of CD4⁺ T helper cells. Therefore, MHC class II molecules are central to effective adaptive immune responses, but conversely, genetic and epidemiological data have im...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
Macmillan Publishers Ltd.
2006
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Subjects: |
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