High-content screening identifies a role for Na+ channels in insulin production

Insulin production is the central feature of functionally mature and differentiated pancreatic β-cells. Reduced insulin transcription and dedifferentiation have been implicated in type 2 diabetes, making drugs that could reverse these processes potentially useful. We have previously established rati...

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Bibliographic Details
Main Authors: Szabat, M, Modi, H, Ramracheya, R, Girbinger, V, Chan, F, Lee, J, Piske, M, Kamal, S, Carol Yang, Y, Welling, A, Rorsman, P, Johnson, J
Format: Journal article
Language:English
Published: Royal Society 2015