EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.

We have used EM visualization of active genes on plasmid vectors in Xenopus oocyte nuclei to investigate the relationship between poly(A) signals and RNA polymerase II transcription termination. Although a functional poly(A) signal is required for efficient termination, cotranscriptional RNA cleavag...

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Những tác giả chính: Osheim, Y, Proudfoot, N, Beyer, A
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1999