Resistance of transmitted founder HIV-1 to IFITM-mediated restriction
Interferon-induced transmembrane proteins (IFITMs) restrict the entry of diverse enveloped viruses through incompletely understood mechanisms. While IFITMs are reported to inhibit HIV-1, their in vivo relevance is unclear. We show that IFITM sensitivity of HIV-1 strains is determined by the co-recep...
| Main Authors: | , , , , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
Cell Press
2016
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