Investigating molecular mechanisms of Dali, an intergenic chromatin-associated lincRNA regulating genes locally and neural differentiation genome-wide

<p>Recently, long non-coding RNAs (lncRNAs) emerged as important regulators of many cellular functions. Many nuclear lncRNAs regulate the expression of geomically proximal or overlapping protein coding genes. Less clear is whether intergenic lncRNAs can regulate transcription by modulating chr...

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Bibliographic Details
Main Author: Chalei, V
Other Authors: Ponting, C
Format: Thesis
Language:English
Published: 2014
Subjects: