The biosafety research road map: the search for evidence to support practices in the laboratory—Foot and Mouth disease virus
<p><strong>Introduction:</strong> Foot and mouth disease (FMD) is a highly contagious infection of cloven-hoofed animals. The Biosafety Research Road Map reviewed scientific literature regarding the foot and mouth disease virus (FMDV). This project aims to identify gaps in the data...
Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Journal article |
Language: | English |
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Mary Ann Liebert Inc.
2023
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author | Blacksell, SD Dhawan, S Kusumoto, M Le, KK Summermatter, K O'Keefe, J Kozlovac, J Almuhairi, SS Sendow, I Scheel, CM Ahumibe, A Masuku, ZM Bennett, AM Kojima, K Harper, DR Hamilton, K |
author_facet | Blacksell, SD Dhawan, S Kusumoto, M Le, KK Summermatter, K O'Keefe, J Kozlovac, J Almuhairi, SS Sendow, I Scheel, CM Ahumibe, A Masuku, ZM Bennett, AM Kojima, K Harper, DR Hamilton, K |
author_sort | Blacksell, SD |
collection | OXFORD |
description | <p><strong>Introduction:</strong> Foot and mouth disease (FMD) is a highly contagious infection of cloven-hoofed animals. The Biosafety Research Road Map reviewed scientific literature regarding the foot and mouth disease virus (FMDV). This project aims to identify gaps in the data required to conduct evidence-based biorisk assessments, as described by Blacksell et al., and strengthen control measures appropriate for local and national laboratories.</p>
<p><strong>Methods:</strong> A literature search was conducted to identify potential gaps in biosafety and focused on five main sections: the route of inoculation/modes of transmission, infectious dose, laboratory-acquired infections, containment releases, and disinfection and decontamination strategies.</p>
<p><strong>Results:</strong> The available data regarding biosafety knowledge gaps and existing evidence have been collated. Some gaps include the need for more scientific data that identify the specific safety contribution of engineering controls, support requirements for showering out after in vitro laboratory work, and whether a 3- to 5-day quarantine period should be applied to individuals conducting in vitro versus in vivo work. Addressing these gaps will contribute to the remediation and improvement of biosafety and biosecurity systems when working with FMDV.</p> |
first_indexed | 2024-03-07T08:21:57Z |
format | Journal article |
id | oxford-uuid:9c36e97d-54e4-4d04-bc42-62017322e005 |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T08:21:57Z |
publishDate | 2023 |
publisher | Mary Ann Liebert Inc. |
record_format | dspace |
spelling | oxford-uuid:9c36e97d-54e4-4d04-bc42-62017322e0052024-02-01T08:40:28ZThe biosafety research road map: the search for evidence to support practices in the laboratory—Foot and Mouth disease virusJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9c36e97d-54e4-4d04-bc42-62017322e005EnglishSymplectic ElementsMary Ann Liebert Inc.2023Blacksell, SDDhawan, SKusumoto, MLe, KKSummermatter, KO'Keefe, JKozlovac, JAlmuhairi, SSSendow, IScheel, CMAhumibe, AMasuku, ZMBennett, AMKojima, KHarper, DRHamilton, K<p><strong>Introduction:</strong> Foot and mouth disease (FMD) is a highly contagious infection of cloven-hoofed animals. The Biosafety Research Road Map reviewed scientific literature regarding the foot and mouth disease virus (FMDV). This project aims to identify gaps in the data required to conduct evidence-based biorisk assessments, as described by Blacksell et al., and strengthen control measures appropriate for local and national laboratories.</p> <p><strong>Methods:</strong> A literature search was conducted to identify potential gaps in biosafety and focused on five main sections: the route of inoculation/modes of transmission, infectious dose, laboratory-acquired infections, containment releases, and disinfection and decontamination strategies.</p> <p><strong>Results:</strong> The available data regarding biosafety knowledge gaps and existing evidence have been collated. Some gaps include the need for more scientific data that identify the specific safety contribution of engineering controls, support requirements for showering out after in vitro laboratory work, and whether a 3- to 5-day quarantine period should be applied to individuals conducting in vitro versus in vivo work. Addressing these gaps will contribute to the remediation and improvement of biosafety and biosecurity systems when working with FMDV.</p> |
spellingShingle | Blacksell, SD Dhawan, S Kusumoto, M Le, KK Summermatter, K O'Keefe, J Kozlovac, J Almuhairi, SS Sendow, I Scheel, CM Ahumibe, A Masuku, ZM Bennett, AM Kojima, K Harper, DR Hamilton, K The biosafety research road map: the search for evidence to support practices in the laboratory—Foot and Mouth disease virus |
title | The biosafety research road map: the search for evidence to support practices in the laboratory—Foot and Mouth disease virus |
title_full | The biosafety research road map: the search for evidence to support practices in the laboratory—Foot and Mouth disease virus |
title_fullStr | The biosafety research road map: the search for evidence to support practices in the laboratory—Foot and Mouth disease virus |
title_full_unstemmed | The biosafety research road map: the search for evidence to support practices in the laboratory—Foot and Mouth disease virus |
title_short | The biosafety research road map: the search for evidence to support practices in the laboratory—Foot and Mouth disease virus |
title_sort | biosafety research road map the search for evidence to support practices in the laboratory foot and mouth disease virus |
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