Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo.

Bisphosphonates are widely used antiresorptive drugs that bind to calcium. It has become evident that these drugs have differing affinities for bone mineral; however, it is unclear whether such differences affect their distribution on mineral surfaces. In this study, fluorescent conjugates of risedr...

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Main Authors: Roelofs, A, Stewart, C, Sun, S, Błażewska, K, Kashemirov, B, McKenna, C, Russell, R, Rogers, M, Lundy, M, Ebetino, F, Coxon, F
格式: Journal article
语言:English
出版: 2012