Targeting free prostate-specific antigen for in vivo imaging of prostate cancer using a monoclonal antibody specific for unique epitopes accessible on free prostate-specific antigen alone.

This study investigated the feasibility of targeting the free, unbound forms of prostate-specific antigen (fPSA) for in vivo imaging of prostate adenocarcinomas (PCa), as PSA is produced and secreted at abundance during every clinical stage and grade of PCa, including castration-resistant disease. W...

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Main Authors: Evans-Axelsson, S, Ulmert, D, Örbom, A, Peterson, P, Nilsson, O, Wennerberg, J, Strand, J, Wingårdh, K, Olsson, T, Hagman, Z, Tolmachev, V, Bjartell, A, Lilja, H, Strand, SE
格式: Journal article
語言:English
出版: 2012

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