The antidotal effect of alpha-1-acid glycoprotein on amitriptyline toxicity in cardiac myocytes
Tricyclic antidepressants in overdose cause toxicity marked by prolongation of the QRS interval of the electrocardiogram. These drugs are bound to α1-acid glycoprotein (AAG) with high affinity in plasma. Animal studies have shown that the administration of AAG shortens the QRS prolongation induced b...
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| Format: | Journal article |
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Elsevier
2001
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