Development and application of computational methods to study DNA modifications

<p>The epigenetic modifications of DNA shape cell fate in development, differentiation, and disease. The existing gold standard sequencing technologies for epigenetic DNA modifications are based on sodium bisulfite, which is a harsh chemical treatment resulting in DNA degradation. A novel bisu...

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Bibliographic Details
Main Author: Velikova, GV
Other Authors: Schuster-Böckler, B
Format: Thesis
Language:English
Published: 2020
Subjects: