Development of a recombinant cell-based system for the characterisation of phosphodiesterase 4 isoforms and evaluation of inhibitors.

We described the development of a recombinant cell-based system for the characterisation of phosphodiesterase (PDE) 4 isoforms and the evaluation of inhibitors. The Chinese hamster ovary (CHO) cell, which was found to have a low endogenous PDE4 background and no beta-adrenergic receptors (beta-AR),...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Allen, R, Merriman, M, Perry, M, Owens, R
التنسيق: Journal article
اللغة:English
منشور في: 1999