The fitness of human translocation carriers.
A simple method to estimate the mean fitness of human translocation carriers is described. The method is based on information about the inheritance pattern of the translocations. This kind of data can be obtained from the surveys of the chromosome constitutions of new-born babies. The following fitn...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1976
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| _version_ | 1797084689927766016 |
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| author | Bengtsson, B Bodmer, W |
| author_facet | Bengtsson, B Bodmer, W |
| author_sort | Bengtsson, B |
| collection | OXFORD |
| description | A simple method to estimate the mean fitness of human translocation carriers is described. The method is based on information about the inheritance pattern of the translocations. This kind of data can be obtained from the surveys of the chromosome constitutions of new-born babies. The following fitness estimates are obtained: D/D translocation carriers, 0-94; D/G translocation carriers, 0-83; and reciprocal translocation carriers, 0-67. The estimates are rather uncertain due to the scarcity of information, but they are consistent with the expected results. More accurate estimates will be obtained in the future when more data on translocation carriers are available and the cytological classification of the different translocations becomes more exact. |
| first_indexed | 2024-03-07T01:58:33Z |
| format | Journal article |
| id | oxford-uuid:9c927be4-8df5-4a6a-a510-e54e0789d201 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:58:33Z |
| publishDate | 1976 |
| record_format | dspace |
| spelling | oxford-uuid:9c927be4-8df5-4a6a-a510-e54e0789d2012022-03-27T00:36:56ZThe fitness of human translocation carriers.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9c927be4-8df5-4a6a-a510-e54e0789d201EnglishSymplectic Elements at Oxford1976Bengtsson, BBodmer, WA simple method to estimate the mean fitness of human translocation carriers is described. The method is based on information about the inheritance pattern of the translocations. This kind of data can be obtained from the surveys of the chromosome constitutions of new-born babies. The following fitness estimates are obtained: D/D translocation carriers, 0-94; D/G translocation carriers, 0-83; and reciprocal translocation carriers, 0-67. The estimates are rather uncertain due to the scarcity of information, but they are consistent with the expected results. More accurate estimates will be obtained in the future when more data on translocation carriers are available and the cytological classification of the different translocations becomes more exact. |
| spellingShingle | Bengtsson, B Bodmer, W The fitness of human translocation carriers. |
| title | The fitness of human translocation carriers. |
| title_full | The fitness of human translocation carriers. |
| title_fullStr | The fitness of human translocation carriers. |
| title_full_unstemmed | The fitness of human translocation carriers. |
| title_short | The fitness of human translocation carriers. |
| title_sort | fitness of human translocation carriers |
| work_keys_str_mv | AT bengtssonb thefitnessofhumantranslocationcarriers AT bodmerw thefitnessofhumantranslocationcarriers AT bengtssonb fitnessofhumantranslocationcarriers AT bodmerw fitnessofhumantranslocationcarriers |