Towards the targeted modulation of gene expression by modified triplex-forming oligonucleotides

Towards the targeted modulation of gene expression by modified triplex-forming oligonucleotides

DNA triple helices are formed when a third nucleic acid strand binds within the major groove of a DNA duplex. The formation of these structures can be used to achieve selective recognition of extended DNA sequences, which may be useful in several medical and biotechnological applications. Although t...

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Bibliographic Details
Main Authors:	Rusling, D, Broughton-Head, V, Brown, T, Fox, K
Format:	Journal article
Language:	English
Published:	2008

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