Towards the targeted modulation of gene expression by modified triplex-forming oligonucleotides
DNA triple helices are formed when a third nucleic acid strand binds within the major groove of a DNA duplex. The formation of these structures can be used to achieve selective recognition of extended DNA sequences, which may be useful in several medical and biotechnological applications. Although t...
Hlavní autoři: | Rusling, D, Broughton-Head, V, Brown, T, Fox, K |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2008
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