Effect of the Putative Lithium Mimetic Ebselen on Brain Myo-Inositol, Sleep, and Emotional Processing in Humans
Lithium remains the gold standard in treating bipolar disorder but has unwanted toxicity and side effects. We previously reported that ebselen inhibits inositol monophosphatase (IMPase) and exhibits lithium-like effects in animal models through lowering of inositol. Ebselen has been tested in clinic...
Main Authors: | Singh, N, Sharpley, A, Emir, U, Masaki, C, Herzallah, M, Gluck, M, Sharp, T, Harmer, C, Vasudevan, S, Cowen, P, Churchill, G |
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Format: | Journal article |
Published: |
Nature Publishing Group
2015
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