Identifying small-effect genetic associations overlooked by the conventional fixed-effect model in a large-scale meta-analysis of coronary artery disease

<p><strong>Motivation:</strong><br/> Common small-effect genetic variants that contribute to human complex traits and disease are typically identified using traditional fixed-effect meta-analysis methods. However, the power to detect genetic associations under fixed-effect mo...

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Autori principali: Magosi, LE, Goel, A, Hopewell, JC, Farrall, M
Altri autori: The Cardiogramplusc4D Consortium
Natura: Journal article
Lingua:English
Pubblicazione: Oxford University Press 2019