Identifying small-effect genetic associations overlooked by the conventional fixed-effect model in a large-scale meta-analysis of coronary artery disease
<p><strong>Motivation:</strong><br/> Common small-effect genetic variants that contribute to human complex traits and disease are typically identified using traditional fixed-effect meta-analysis methods. However, the power to detect genetic associations under fixed-effect mo...
Prif Awduron: | Magosi, LE, Goel, A, Hopewell, JC, Farrall, M |
---|---|
Awduron Eraill: | The Cardiogramplusc4D Consortium |
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
Oxford University Press
2019
|
Eitemau Tebyg
-
Identifying systematic heterogeneity patterns in genetic association meta-analysis studies
gan: Magosi, L, et al.
Cyhoeddwyd: (2017) -
Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer’s disease
gan: Grace, PC, et al.
Cyhoeddwyd: (2018) -
Large-scale association analysis identifies new risk loci for coronary artery disease.
gan: Deloukas, P, et al.
Cyhoeddwyd: (2013) -
Large-scale association analysis identifies new risk loci for coronary artery disease
gan: Deloukas, P, et al.
Cyhoeddwyd: (2012) -
USE OF ENCODE DATA TO IDENTIFY PUTATIVE FUNCTIONAL VARIANTS IN CORONARY ARTERY DISEASE GWAS
gan: Goel, A, et al.
Cyhoeddwyd: (2014)