Identifying small-effect genetic associations overlooked by the conventional fixed-effect model in a large-scale meta-analysis of coronary artery disease
<p><strong>Motivation:</strong><br/> Common small-effect genetic variants that contribute to human complex traits and disease are typically identified using traditional fixed-effect meta-analysis methods. However, the power to detect genetic associations under fixed-effect mo...
Κύριοι συγγραφείς: | Magosi, LE, Goel, A, Hopewell, JC, Farrall, M |
---|---|
Άλλοι συγγραφείς: | The Cardiogramplusc4D Consortium |
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
Oxford University Press
2019
|
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
Identifying systematic heterogeneity patterns in genetic association meta-analysis studies
ανά: Magosi, L, κ.ά.
Έκδοση: (2017) -
Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer’s disease
ανά: Grace, PC, κ.ά.
Έκδοση: (2018) -
Large-scale association analysis identifies new risk loci for coronary artery disease.
ανά: Deloukas, P, κ.ά.
Έκδοση: (2013) -
Large-scale association analysis identifies new risk loci for coronary artery disease
ανά: Deloukas, P, κ.ά.
Έκδοση: (2012) -
USE OF ENCODE DATA TO IDENTIFY PUTATIVE FUNCTIONAL VARIANTS IN CORONARY ARTERY DISEASE GWAS
ανά: Goel, A, κ.ά.
Έκδοση: (2014)