Identifying small-effect genetic associations overlooked by the conventional fixed-effect model in a large-scale meta-analysis of coronary artery disease
<p><strong>Motivation:</strong><br/> Common small-effect genetic variants that contribute to human complex traits and disease are typically identified using traditional fixed-effect meta-analysis methods. However, the power to detect genetic associations under fixed-effect mo...
Автори: | Magosi, LE, Goel, A, Hopewell, JC, Farrall, M |
---|---|
Інші автори: | The Cardiogramplusc4D Consortium |
Формат: | Journal article |
Мова: | English |
Опубліковано: |
Oxford University Press
2019
|
Схожі ресурси
Схожі ресурси
-
Identifying systematic heterogeneity patterns in genetic association meta-analysis studies
за авторством: Magosi, L, та інші
Опубліковано: (2017) -
Lack of genetic support for shared aetiology of Coronary Artery Disease and Late-onset Alzheimer’s disease
за авторством: Grace, PC, та інші
Опубліковано: (2018) -
Large-scale association analysis identifies new risk loci for coronary artery disease.
за авторством: Deloukas, P, та інші
Опубліковано: (2013) -
Large-scale association analysis identifies new risk loci for coronary artery disease
за авторством: Deloukas, P, та інші
Опубліковано: (2012) -
USE OF ENCODE DATA TO IDENTIFY PUTATIVE FUNCTIONAL VARIANTS IN CORONARY ARTERY DISEASE GWAS
за авторством: Goel, A, та інші
Опубліковано: (2014)