111In-labeled immunoconjugates (ICs) bispecific for the epidermal growth factor receptor (EGFR) and cyclin-dependent kinase inhibitor, p27Kip1.

OBJECTIVE: Probing intranuclear proteins in breast cancer (BC) cells by using radiolabeled antibodies is restricted by delivery barriers presented by cell and nuclear membranes. Our aim was to construct immunoconjugates (ICs) bispecific for epidermal growth factor receptors (EGFRs) and the intranuc...

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Bibliographic Details
Main Authors: Cornelissen, B, Kersemans, V, McLarty, K, Tran, L, Reilly, R
Format: Journal article
Language:English
Published: 2009