HR23B, a biomarker for HDAC inhibitors

HR23B, a biomarker for HDAC inhibitors

<p>As our understanding of cancer biology increases and novel therapies are developed, an increasing number of predictive biomarkers are becoming clinically available. Aberrant acetylation has been strongly linked to tumourigenesis and the modulation of acetylation through targeting histone d...

Descripció completa

Dades bibliogràfiques
Autor principal:	Khan, OA
Altres autors:	La Thangue, NB
Format:	Thesis
Idioma:	English
Publicat:	2013
Matèries:	Pharmacology Tumours Clinical laboratory sciences Medical Sciences Oncology

Ítems similars

Mitochondrial modulators of hypoxia-related pathways in tumours
per: Snell, CE
Publicat: (2013)

Role of HR23B, HDAC6 and Myd88 and their interplay in response to HDAC inhibitor treatment
per: New, M
Publicat: (2014)

Angiogenesis in human lung tumours
per: Ferguson, ML
Publicat: (2008)

Risk factors for haemorrhage in patients with haematological malignancies
per: Estcourt, LJ
Publicat: (2014)

Regulation of stemness and differentiation in colorectal cancer
per: Gandhi, S
Publicat: (2010)

Development of sindbis virus as an oncolytic agent
per: Kueberuwa, GLB
Publicat: (2012)

Tumour-stroma interaction in pancreatic cancer
per: Lunardi, S
Publicat: (2013)

Targeting EGFR signalling pathway in triple negative breast cancer
per: Albukhari, A
Publicat: (2014)

Targeting EGFR signalling pathway in triple negative breast cancer
per: Albukhari, A
Publicat: (2014)

Characterising the role of circulating immune cells in brain metastasis
per: Balathasan, L
Publicat: (2012)

The role of ATF4 in hypoxia-induced cell death in cancer
per: Pike, L, et al.
Publicat: (2011)

Combining regulatory angiogenic gene therapy and virotherapy for the treatment of breast cancer
per: Bazan Peregrino, M
Publicat: (2007)

Modulating the immune system by amino acid depletion - IDO and beyond
per: Vallius, L
Publicat: (2011)

Novel signalling pathways regulating epithelial-mesenchymal transition in bone metastatic prostate cancer
per: Rao, SR
Publicat: (2014)

Arginine methylation in the E2F1 pathway
per: Zheng, S
Publicat: (2013)

Investigating a role of ASPP2 in the cellular response to infection
per: Lim, Y, et al.
Publicat: (2014)

Development of models and methods to assess the efficacy of anti-cancer drugs targeted to the mitochondria
per: Potter, M
Publicat: (2014)

Improving intraperitoneal adenovirus virotherapy for ovarian cancer
per: Thoma, CMM
Publicat: (2011)

HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy.
per: Khan, O, et al.
Publicat: (2010)

The role of host microenvironment in the pathogenesis of multiple myeloma
per: Lwin, STS
Publicat: (2014)

Targeting polymer coated adenovirus to tumour-associated vasculature
per: Bachtarzi, H
Publicat: (2010)

Managing melanoma in the era of personalised therapy: more than one disease
per: Rughani, M, et al.
Publicat: (2012)

Loss of chaperone protein in human cancer
per: Adighibe, O
Publicat: (2012)

Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes
per: Wijeyekoon, JB
Publicat: (2013)

Tolerance in renal transplantation: is mixed chimerism the missing link?
per: Janes, S, et al.
Publicat: (2009)

The role of DLL4-NOTCH signalling in endothelial cell metabolism
per: Harjes, U
Publicat: (2014)

The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy
per: Jackson, M
Publicat: (2013)

The role of HER4 in relation to trastuzumab resistance and prognosis in HER2 positive breast cancer
per: Mohd Nafi, SN
Publicat: (2014)

Development of clinical biomarkers of DNA double strand breaks for cancer care
per: Shah, K
Publicat: (2012)

Biomarkers of anti-angiogenic therapy in breast cancer
per: Mehta, S
Publicat: (2014)

Development of bioreductive inhibitors of checkpoint kinase 1 to target hypoxic tumours
per: Körner, C
Publicat: (2015)

Selective targeting of homologous recombination deficiency
per: Zimmer, J
Publicat: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
per: Pfister, SX
Publicat: (2014)

Impact of TMPRSS2-ERG fusion gene on prostate cancer cell response to chemotherapy, radiotherapy and androgen deprivation therapy
per: Ovtcharov, S
Publicat: (2015)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
per: Phipps, L
Publicat: (2011)

Cortical dynamics subserving visual apparent motion
per: Ahmed, B, et al.
Publicat: (2008)

Investigating the endogenous role of human n-acetyltransferase 1, as potential breast cancer biomarker, using chemical biology
per: Laurieri, N
Publicat: (2012)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
per: Ledaki, I
Publicat: (2013)

A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors.
per: New, M, et al.
Publicat: (2013)

A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors
per: New, M, et al.
Publicat: (2013)