HR23B, a biomarker for HDAC inhibitors

HR23B, a biomarker for HDAC inhibitors

<p>As our understanding of cancer biology increases and novel therapies are developed, an increasing number of predictive biomarkers are becoming clinically available. Aberrant acetylation has been strongly linked to tumourigenesis and the modulation of acetylation through targeting histone d...

Bibliografski detalji
Glavni autor:	Khan, OA
Daljnji autori:	La Thangue, NB
Format:	Disertacija
Jezik:	English
Izdano:	2013
Teme:	Pharmacology Tumours Clinical laboratory sciences Medical Sciences Oncology

Slični predmeti

Mitochondrial modulators of hypoxia-related pathways in tumours
od: Snell, CE
Izdano: (2013)

Role of HR23B, HDAC6 and Myd88 and their interplay in response to HDAC inhibitor treatment
od: New, M
Izdano: (2014)

Angiogenesis in human lung tumours
od: Ferguson, ML
Izdano: (2008)

Risk factors for haemorrhage in patients with haematological malignancies
od: Estcourt, LJ
Izdano: (2014)

Regulation of stemness and differentiation in colorectal cancer
od: Gandhi, S
Izdano: (2010)

Development of sindbis virus as an oncolytic agent
od: Kueberuwa, GLB
Izdano: (2012)

Tumour-stroma interaction in pancreatic cancer
od: Lunardi, S
Izdano: (2013)

Targeting EGFR signalling pathway in triple negative breast cancer
od: Albukhari, A
Izdano: (2014)

Targeting EGFR signalling pathway in triple negative breast cancer
od: Albukhari, A
Izdano: (2014)

Characterising the role of circulating immune cells in brain metastasis
od: Balathasan, L
Izdano: (2012)

The role of ATF4 in hypoxia-induced cell death in cancer
od: Pike, L, i dr.
Izdano: (2011)

Combining regulatory angiogenic gene therapy and virotherapy for the treatment of breast cancer
od: Bazan Peregrino, M
Izdano: (2007)

Modulating the immune system by amino acid depletion - IDO and beyond
od: Vallius, L
Izdano: (2011)

Novel signalling pathways regulating epithelial-mesenchymal transition in bone metastatic prostate cancer
od: Rao, SR
Izdano: (2014)

Arginine methylation in the E2F1 pathway
od: Zheng, S
Izdano: (2013)

Investigating a role of ASPP2 in the cellular response to infection
od: Lim, Y, i dr.
Izdano: (2014)

Development of models and methods to assess the efficacy of anti-cancer drugs targeted to the mitochondria
od: Potter, M
Izdano: (2014)

Improving intraperitoneal adenovirus virotherapy for ovarian cancer
od: Thoma, CMM
Izdano: (2011)

HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy.
od: Khan, O, i dr.
Izdano: (2010)

The role of host microenvironment in the pathogenesis of multiple myeloma
od: Lwin, STS
Izdano: (2014)

Targeting polymer coated adenovirus to tumour-associated vasculature
od: Bachtarzi, H
Izdano: (2010)

Managing melanoma in the era of personalised therapy: more than one disease
od: Rughani, M, i dr.
Izdano: (2012)

Loss of chaperone protein in human cancer
od: Adighibe, O
Izdano: (2012)

Tissue expression and functional insights into HIF prolyl hydroxylase domain enzymes
od: Wijeyekoon, JB
Izdano: (2013)

Tolerance in renal transplantation: is mixed chimerism the missing link?
od: Janes, S, i dr.
Izdano: (2009)

The role of DLL4-NOTCH signalling in endothelial cell metabolism
od: Harjes, U
Izdano: (2014)

The identification and validation of Auger electron-emitting radiopharmaceuticals targeting telomerase for cancer therapy
od: Jackson, M
Izdano: (2013)

The role of HER4 in relation to trastuzumab resistance and prognosis in HER2 positive breast cancer
od: Mohd Nafi, SN
Izdano: (2014)

Development of clinical biomarkers of DNA double strand breaks for cancer care
od: Shah, K
Izdano: (2012)

Biomarkers of anti-angiogenic therapy in breast cancer
od: Mehta, S
Izdano: (2014)

Development of bioreductive inhibitors of checkpoint kinase 1 to target hypoxic tumours
od: Körner, C
Izdano: (2015)

Selective targeting of homologous recombination deficiency
od: Zimmer, J
Izdano: (2014)

The three methyls: the function and therapeutic potential of histone H3K36 trimethylation
od: Pfister, SX
Izdano: (2014)

Impact of TMPRSS2-ERG fusion gene on prostate cancer cell response to chemotherapy, radiotherapy and androgen deprivation therapy
od: Ovtcharov, S
Izdano: (2015)

Targeting cell adhesion as a method of sensitising metastatic tumour cells to TRAIL-induced apoptosis
od: Phipps, L
Izdano: (2011)

Cortical dynamics subserving visual apparent motion
od: Ahmed, B, i dr.
Izdano: (2008)

Investigating the endogenous role of human n-acetyltransferase 1, as potential breast cancer biomarker, using chemical biology
od: Laurieri, N
Izdano: (2012)

Heterogeneity of tumour response to hypoxia: carbonic anhydrase IX induction defines a subpopulation of hypoxic cells with stem cell properties and drug resistance
od: Ledaki, I
Izdano: (2013)

A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors.
od: New, M, i dr.
Izdano: (2013)

A regulatory circuit that involves HR23B and HDAC6 governs the biological response to HDAC inhibitors
od: New, M, i dr.
Izdano: (2013)