Enhanced anti-HIV functional activity associated with Gag-specific CD8 T-cell responses.

Effective HIV-specific T-cell immunity requires the ability to inhibit virus replication in the infected host, but the functional characteristics of cells able to mediate this effect are not well defined. Since Gag-specific CD8 T cells have repeatedly been associated with lower viremia, we examined...

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Detalhes bibliográficos
Main Authors: Julg, B, Williams, K, Reddy, S, Bishop, K, Qi, Y, Carrington, M, Goulder, P, Ndung'u, T, Walker, B
Formato: Journal article
Idioma:English
Publicado em: 2010