Enhanced in vivo antitumor efficacy of dual-functional peptide-modified docetaxel nanoparticles through tumor targeting and Hsp90 inhibition

Although conventional anticancer drugs exhibit excellent efficacy, serious adverse effects and/or even toxicity have occurred due to their nonselectivity. Moreover, active targeting approaches have not consistently led to successful outcomes. Ligands that simultaneously possess targeting capability...

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Bibliographic Details
Main Authors: Jiang, Y, Yang, N, Zhang, H, Sun, B, Hou, C, Ji, C, Zheng, J, Liu, Y, Zuo, P
Format: Journal article
Language:English
Published: Elsevier 2015