Towards a TDP-43-based biomarker for ALS and FTLD

Towards a TDP-43-based biomarker for ALS and FTLD

TDP-43 accumulates in nerve cells of nearly all cases of amyotrophic lateral sclerosis (ALS, the commonest form of motor neuron disease) and in the majority of Tau-negative frontotemporal lobar degeneration (FTLD). There is currently no biochemical test or marker of disease activity for ALS or FTLD...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Feneberg, E, Gray, E, Ansorge, O, Talbot, K, Turner, M
Fformat:	Journal article
Cyhoeddwyd:	Springer US 2018

Eitemau Tebyg

Detection and quantification of novel C-terminal TDP-43 fragments in ALS-TDP
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TDP-43 based biomarker development in amyotrophic lateral sclerosis
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Publisher Correction to: Diffuse argyrophilic grain disease with TDP-43 proteinopathy and neuronal intermediate filament inclusion disease: FTLD with mixed tau, TDP-43 and FUS pathologies
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LIPIDS ALTERATION IN TDP-43
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A C-Terminally Truncated TDP-43 Splice Isoform Exhibits Neuronal Specific Cytoplasmic Aggregation and Contributes to TDP-43 Pathology in ALS
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TDP-43 Cytoplasmic Translocation in the Skin Fibroblasts of ALS Patients
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