Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection.

Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection.

BACKGROUND: The HLA class II molecules play a central role in the generation of human immunodeficiency virus (HIV)-specific CD4(+) T-helper cells, which are critical for the induction of cytotoxic CD8(+) T cell responses. However, little is known about the impact of HLA class II alleles on HIV disea...

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Autors principals:	Julg, B, Moodley, E, Qi, Y, Ramduth, D, Reddy, S, Mncube, Z, Gao, X, Goulder, P, Detels, R, Ndung'u, T, Walker, B, Carrington, M
Format:	Journal article
Idioma:	English
Publicat:	2011

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