The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.

Orthogonal and modular templating is an effective basis for the preparation of the biologically active annonaceous acetogenin 10-hydroxyasimicin (1). The versatile tartrate-derived 2,3-butanediacetal building block together with a highly diastereoselective hetero-Diels-Alder approach to the butenoli...

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Main Authors: Nattrass, G, Díez, E, McLachlan, M, Dixon, D, Ley, S
Format: Journal article
Language:English
Published: 2005
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author Nattrass, G
Díez, E
McLachlan, M
Dixon, D
Ley, S
author_facet Nattrass, G
Díez, E
McLachlan, M
Dixon, D
Ley, S
author_sort Nattrass, G
collection OXFORD
description Orthogonal and modular templating is an effective basis for the preparation of the biologically active annonaceous acetogenin 10-hydroxyasimicin (1). The versatile tartrate-derived 2,3-butanediacetal building block together with a highly diastereoselective hetero-Diels-Alder approach to the butenolide unit were usefully employed in this novel synthetic route.
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spelling oxford-uuid:9da7f136-6347-4ae4-a155-02d280ad8cdf2022-03-27T00:44:35ZThe total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9da7f136-6347-4ae4-a155-02d280ad8cdfEnglishSymplectic Elements at Oxford2005Nattrass, GDíez, EMcLachlan, MDixon, DLey, SOrthogonal and modular templating is an effective basis for the preparation of the biologically active annonaceous acetogenin 10-hydroxyasimicin (1). The versatile tartrate-derived 2,3-butanediacetal building block together with a highly diastereoselective hetero-Diels-Alder approach to the butenolide unit were usefully employed in this novel synthetic route.
spellingShingle Nattrass, G
Díez, E
McLachlan, M
Dixon, D
Ley, S
The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.
title The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.
title_full The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.
title_fullStr The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.
title_full_unstemmed The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.
title_short The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.
title_sort total synthesis of the annonaceous acetogenin 10 hydroxyasimicin
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