The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.
Orthogonal and modular templating is an effective basis for the preparation of the biologically active annonaceous acetogenin 10-hydroxyasimicin (1). The versatile tartrate-derived 2,3-butanediacetal building block together with a highly diastereoselective hetero-Diels-Alder approach to the butenoli...
Main Authors: | , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2005
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author | Nattrass, G Díez, E McLachlan, M Dixon, D Ley, S |
author_facet | Nattrass, G Díez, E McLachlan, M Dixon, D Ley, S |
author_sort | Nattrass, G |
collection | OXFORD |
description | Orthogonal and modular templating is an effective basis for the preparation of the biologically active annonaceous acetogenin 10-hydroxyasimicin (1). The versatile tartrate-derived 2,3-butanediacetal building block together with a highly diastereoselective hetero-Diels-Alder approach to the butenolide unit were usefully employed in this novel synthetic route. |
first_indexed | 2024-03-07T02:01:53Z |
format | Journal article |
id | oxford-uuid:9da7f136-6347-4ae4-a155-02d280ad8cdf |
institution | University of Oxford |
language | English |
last_indexed | 2024-03-07T02:01:53Z |
publishDate | 2005 |
record_format | dspace |
spelling | oxford-uuid:9da7f136-6347-4ae4-a155-02d280ad8cdf2022-03-27T00:44:35ZThe total synthesis of the annonaceous acetogenin 10-hydroxyasimicin.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9da7f136-6347-4ae4-a155-02d280ad8cdfEnglishSymplectic Elements at Oxford2005Nattrass, GDíez, EMcLachlan, MDixon, DLey, SOrthogonal and modular templating is an effective basis for the preparation of the biologically active annonaceous acetogenin 10-hydroxyasimicin (1). The versatile tartrate-derived 2,3-butanediacetal building block together with a highly diastereoselective hetero-Diels-Alder approach to the butenolide unit were usefully employed in this novel synthetic route. |
spellingShingle | Nattrass, G Díez, E McLachlan, M Dixon, D Ley, S The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin. |
title | The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin. |
title_full | The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin. |
title_fullStr | The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin. |
title_full_unstemmed | The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin. |
title_short | The total synthesis of the annonaceous acetogenin 10-hydroxyasimicin. |
title_sort | total synthesis of the annonaceous acetogenin 10 hydroxyasimicin |
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